WARNING/Warning: Regardless that it may be unusual, a lot of people may have extremely undesirable and from time to time fatal Unwanted effects when taking a drug. Convey to your physician or get clinical assistance immediately For those who have any of the next indications or signs or symptoms Which might be connected to an exceedingly bad side result:

C: Use with caution if Positive aspects outweigh pitfalls. Animal reports demonstrate chance and human reports not out there or neither animal nor human experiments carried out.

Serotonin: Modafinil is thought to extend amounts of serotonin, a neurotransmitter essential for regulating mood by stimulating the serotonergic program from the cortex, hypothalamus, and amygdala.

No unique dose adjustment encouraged when tofacitinib coadministered with powerful CYP2C19 inhibitors; decrease tofacitinib dose if coadministered with each reasonable CYP3A4 and potent CYP2C19 inhibitors .

acetazolamide will improve the level or effect of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.

Watch Carefully (one)modafinil will improve the amount or result of flibanserin by impacting hepatic enzyme CYP2C19 metabolism.

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Stiripentol is actually a CYP3A4 inhibitor and inducer. Check CYP3A4 substrates coadministered with stiripentol for elevated or decreased consequences. CYP3A4 substrates may well call for dosage adjustment.

Modafinil may cause pores and skin reactions That could be intense ample to need cure inside a healthcare facility. Cease having this drugs and get crisis health-related aid For those who have:

tecovirimat will increase the level or outcome of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Check. Tecovirimat is usually a weak inhibitor of CYP2C8 and CYP2C19. Monitor for adverse consequences if coadministered with delicate substrates of those enzymes.

cannabidiol will boost the degree or result of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Watch Intently. Take into consideration reducing the dose of sensitive CYP2C19 substrates, as clinically correct, when coadministered with cannabidiol.

Even though significantly less typical, quite possibly the most read more significant side effects of modafinil are explained down below, coupled with what to do whenever they happen.

istradefylline will boost the amount or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

Shift work dysfunction, a ailment (mainly in men and women Doing the job night time, early early morning, or rotating shifts) involving trouble sleeping when you have to and/or Severe sleepiness when you must be awake